![]() The method generates quantitative T1 maps with an in-plane resolution of 1 mm, slice thickness of 4 mm, and whole-brain coverage in a clinically acceptable imaging time of about 19 s per slice. This allows for a reduction of the total acquisition time, or scanning with a reduced bandwidth, which improves the signal-to-noise ratio (SNR). Furthermore, it is possible to acquire data during all relaxation delays because only slice-selective radiofrequency (RF) pulses are used for inversion and excitation. In contrast to similar methods, no saturation pulses are used, resulting in an increased dynamic range of the relaxation process. A sequence for the acquisition of high-resolution T1 maps, based on magnetization-prepared multislice fast low-angle shot (FLASH) imaging, is presented.
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